Job Summary

An open position for a Research Associate under the supervision of Dr. Huiyuan Wu is available in the Department of Pediatrics. We are seeking an energetic, highly motivated individual to join our team to develop small molecule therapies for rare diseases that currently have no treatment. The candidate will cooperate with the Structural Biology team to determine the lead-target interaction and evaluate the effectiveness of compounds in the mouse models of diseases. As part of small molecule therapy development team with special interests in rare diseases, this position offers opportunities to interact with highly experienced basic scientists and physician scientists, and gain research skills in structural biology, genetic mouse models, biochemistry, cell biology, and physiology. This position may be transferred to a permanent position after 1 year.

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Work at Michigan?

Being part of something greater, of serving a larger mission of discovery and care ? that's the heart of what drives people to work at Michigan. In some way, great or small, every person here helps to advance this world-class institution. It's adding a purpose to your profession. Work at Michigan and become a victor for the greater good.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world?s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

Excellent medical, dental and vision coverage effective on your very first day
2:1 Match on retirement savings

Responsibilities*

The Research Associate supports translational research within the Division of Pediatric Nephrology and is expected to understand and support the conduct of research within all federal, state and local regulatory requirements. The candidate will perform independent work under the guidance of the program director, while also collaborating as necessary to support overall program success.

Routine duties include:

Under the direction of study PI to ensure research related procedures are completed in accordance with good practice guidelines.
Molecular cloning, plasmid preparation, DNA and RNA extraction.
Western blotting, PCR, and quantitative RT-PCR.
Cell culture and transfection.
Colony management for genetically manipulated mouse models.
Administration of compounds to the mouse model of diseases.
Mouse tissue collection and histological analysis.
Microscope imaging.
Physiological analysis and behavior tests of the mouse models.
Lab management.
Other duties may have to be performed as assigned necessary to maintain the smooth operation of the research program.

Required Qualifications*

Bachelor's degree in Life Science or an equivalent combination of related education and experience is necessary.
High interest in applying mouse models to identify new therapies for human disease
Applicant should be motivated and willing to learn new techniques and knowledge
Previous hands-on laboratory experience is preferred but not required.
Ability to read literature and implement new procedures in accordance with the supervisor.
Demonstrated ability to work successfully in a research group, team, while meeting deadlines.
Excellent attendance and strong work ethic in past settings
Knowledge of personal computers and Microsoft applications

Desired Qualifications*

Experiences of working with animals

Work Locations

This position will be located at MSRB3

Modes of Work

Positions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modes.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.