Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.
We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.
It is an exciting time of growth for argenx as we strive to achieve our VISION 2030. Vision 2030 is our long-term commitment to transform the treatment of rare and autoimmune diseases by strengthening our leadership in neonatal Fc receptor (FcRn) biology, investing in our continuous pipeline of differentiated antibody candidates, and scaling in a disciplined way to ensure innovation remains core to the argenx mission. ‘Vision 2030’ includes the following goals: 50,000 patients globally on treatment with an argenx medicine, 10 labeled indications across all approved assets, including VYVGART and potentially empasiprubart, ARGX-119 and five new molecules in Phase 3 development.
The Global Medical Indication Lead for a neuromuscular indication: leads the clinical team, translating the Target Product Profile (TPP) as set by the Asset Strategy Team into a Clinical Development Plan that answers the relevant questions safeguarding time, quality and budget, in collaboration with the cross functional team, the Clinical Development Asset Lead and the Asset Strategy Team, in order to maximize the potential of the Asset for the given indication.
Roles and Responsibilities:
Provide continuous strategic medical insight and planning for the indication during all stages of development
Lead the Clinical Development Plan and participate in long range strategic planning as data emerge in the indication
Line management of the Global Clinical Trial Physicians working on the indication: coach and set example for their roles ensuring high quality medical support for the study teams, identify high performers for potential other roles
Real time oversight of the medical aspects of studies in the indication, including the relevant communication to management as well as the different study teams
Safeguard harmonization across the studies so that communications to external stakeholders (e.g. questions of IRBs, are consistent and company efficiency is maintained in close collaboration with peers as well as management of the different functional groups
Lead indication medical ad boards and develop collaborations with external experts as appropriate
Help build and maintain a “best in class” group of development medical doctors
Ensure compliance of all studies in the indication
Closely collaborate with the Clinical Development Asset Lead and other development functions in order for medical vision, risks, issues, and results to be aligned with and clear to all involved parties
Desired Skills and Experience:
Medical Doctor; relevant specialty education preferred, (e.g. neurology, immunology, internal medicine, pediatric), having acquired in-depth understanding of end to end (phase I to registration) drug development based on relevant experience of at least 3-5 years in the pharma/biotech industry, preferably in neuromuscular disease
Excellent English, both written and spoken is a must, as well as ability to travel
Proven leadership, motivational and interpersonal skills in a global and intercultural environment, including leading through influence (without having direct reporting lines) and willingness to grow in responsibility with the company
Pro-active problem solver with negotiation skills
Must provide clear vision, direction, and purpose to the different study teams
Demonstrated expertise in clinical trial design, conduct and interpretation of clinical data
Strong communication skills to ensure that study plans and status are transparent, and that risks, issues, and results are clear to all involved parties. A matrix structure requires additional skills in gathering decision information, negotiation and communicating decisions and action
Executes his/her responsibilities with knowledge, accuracy, persistence, resilience and creativity, being an accomplished team player whilst maintaining medical integrity
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At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.
If you require reasonable accommodation in completing your application, interviewing, or otherwise participating in the candidate selection process please contact us at hr.us@argenx.com. Only inquiries related to an accommodation request will receive a response.
